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Our research projects focus on the molecular mechanism of specificity of signal transduction of seven transmembrane receptors (GPCRs).

Our interests are divided into two main themes:

1) How are homo- and heterodimeric seven transmembrane receptors assembled and trafficked to plasma membrane?

2) How members of a particular receptor complex contribute to specificity of signaling?

We use a combination of biochemical and molecular biology approaches with new tools such as Bimolecular Fluorescence Complementation in combination with BRET or FRET to study the specificify of assembly and trafficking of receptor signaling complexes.