Stradiotto Research Group Organometallic Synthesis and Homogeneous Catalysis
Crystal structure of (Mor-DalPhos)AuCl	Mark Stradiotto, Ph.D. Professor Canada Foundation for Innovation Researcher Dalhousie Killam Research Prize Winner Dalhousie Innovation Award Winner Harry Shirreff Prize for Research Winner Synlett Promising Young Professor Journal Awardee Named to advisory board of “Organometallics” (2010-2013) Faculty of Science Killam Professor (2011-2016) Winner of the 2012 Canadian Society for Chemistry “Strem Chemicals Award for Pure or Applied Inorganic Chemistry” Links: Recent Group News Publications Patents, Funding, and Infrastructure Current and Past Group Info. for Prospective Students Dalhousie Chemistry site last updated on 12-Oct-2012
Selected Representative Recent Publications (click on reference for PDF): A Highly Efficient P,O-DalPhos/Pd Catalyst for Indole Synthesis: Chem. Commun., 2012, 48, 7277–7279. Chemoselective Buchwald-Hartwig aminations Using Mor-DalPhos/Pd: J. Org. Chem., 2012, 77, 1056–1071. Acetone Monoarylation Using Mor-DalPhos/Pd: J. Am. Chem. Soc., 2011, 133, 5194-5197. Ammonia Monoarylation Using Mor-DalPhos/Pd: Angew. Chem. Int. Ed., 2010, 49, 4071-4074. Hydrazine Monoarylation Using Mor-DalPhos/Pd: Angew. Chem. Int. Ed., 2010, 49, 8686-8690. Challenging Alkyne hydroamination Using Mor-DalPhos/Au: J. Am. Chem. Soc., 2010, 132, 18026-18029. Alkene Cyclohydroamination Using [Ir(COD)Cl]2: J. Am. Chem. Soc., 2010, 132, 413-426. **Click here for selected coverage of our work, including in Chemical and Engineering News** DalPhos ligands are now commercially available **Click here for the Strem website; click here for the Aldrich website ** To view this Webinar given by Prof. Stradiotto, please click here (scroll to the bottom, choose media format and select “Launch Presentation”). Research Interests Research efforts in the Stradiotto group are directed toward developing new classes of ancillary ligands/transition metal complexes that exhibit interesting and unusual reactivity patterns, with the goal of incorporating such reactivity into synthetically useful catalytic substrate transformations. Our current research program is focused on the development of: 1. Highly effective ancillary ligands for use in challenging cross-couplings and related substrate transformations. Our work in this area was featured in Chemical and Engineering News; please click here for the articles. 2. New late metal catalyst complexes for the hydroamination of unsaturated substrates. 3. Zwitterionic relatives of more traditional cationic late metal complexes, in anticipation that these may prove useful in a range of catalytic transformations. Central themes that link these various programs include: the establishment of innovative ligation strategies for use in constructing suitably reactive transition metal complexes; the evaluation of structure-activity relationships including mechanistic studies to guide the development of increasingly reactive complexes; and the development of new and synthetically useful substrate transformations.   Visit our publications section for a recent account of the projects ongoing in the group.