Stradiotto Research Group Organometallic Synthesis and Homogeneous Catalysis
Crystal structure of (Mor-DalPhos)AuCl	Mark Stradiotto, Ph.D. Professor Canada Foundation for Innovation Researcher Dalhousie Killam Research Prize Winner Dalhousie Innovation Award Winner Harry Shirreff Prize for Research Winner Synlett Promising Young Professor Journal Awardee Named to advisory board of “Organometallics” (2010-2013) Faculty of Science Killam Professor (2011-2016) Links: Recent Group News Publications Patents, Funding, and Infrastructure Current and Past Group Info. for Prospective Students Dalhousie Chemistry site last updated on 25-October-2011
To view this Webinar given by Prof. Stradiotto, please click here (scroll to the bottom, choose media format and select “Launch Presentation”). Selected Recent Publications (click on reference for PDF): Broadly useful catalyst for Buchwald-Hartwig Amination: Chem. Eur. J., 2010, 16, 1983-1991. Ammonia arylation: Angew. Chem. Int. Ed., 2010, 49, 4071-4074. Hydrazine arylation: Angew. Chem. Int. Ed., 2010, 49, 8686-8690. Alkyne hydroamination with dialkylamines: J. Am. Chem. Soc., 2010, 132, 18026-18029. Alkene cyclohydroamination: J. Am. Chem. Soc., 2010, 132, 413-426. Acetone arylation: J. Am. Chem. Soc., 2011, 133, 5194-5197. Tandem ammonia/hydrazine arylation/hydroamination: Chem. Commun., 2011, 47, 6936–6938. **Click here for selected coverage of our work, including in Chemical and Engineering News** Research Interests Research efforts in the Stradiotto group are directed toward developing new classes of ancillary ligands/transition metal complexes that exhibit interesting and unusual reactivity patterns, with the goal of incorporating such reactivity into synthetically useful catalytic substrate transformations. Our current research program is focused on the development of: 1. Highly effective ancillary ligands for use in challenging Buchwald-Hartwig aminations and related cross-coupling reactions. Our work in this area was featured in Chemical and Engineering News; please click here for the articles. 2. New late metal catalyst complexes for the hydroamination of unsaturated substrates. 3. Zwitterionic relatives of more traditional cationic late metal complexes, in anticipation that these may prove useful in a range of catalytic transformations. Central themes that link these various programs include: the establishment of innovative ligation strategies for use in constructing suitably reactive transition metal complexes; the evaluation of structure-activity relationships including mechanistic studies to guide the development of increasingly reactive complexes; and the development of new and synthetically useful substrate transformations.   Visit our publications section for a recent account of the projects ongoing in the group.