Publications

Taken from "Physical organic chemistry in the making".
By Jan B. F. N. Engberts

I contend that in the future physical organic chemistry will continue to be largely characterized by detailed and quantitative analyses of the effects of structure variation on the properties of molecules and ensembles of molecules. The physical organic chemist will further contribute to developing a sophisticated feeling for what structural perturbation can teach us and will be able to synthesize the compounds necessary for such an approach. I think it is this expertise that clearly distinguishes the physical organic chemist from the physical chemist.

New compounds will become available for probing structure-property relationships and the results will challenge theoretical chemists to employ statistical thermodynamic techniques to model these novel systems. Organic molecules respond to structure variation by exhibiting modifications in reactivity, in spectroscopic properties, in thermodynamic properties, and in many other respects. By identifying structure-property relationships physical organic chemists provide, inter alia, ground rules for specialist synthetic organic chemists in the context of target-synthesis in, for example, the pharmaceutical sciences. In addition, they will provide a major contribution to establishing a firm basis for understanding the relation between molecular structure and physiological action. This subject will become increasingly important in biochemistry and in the medical sciences.

The physical organic chemist will be the scientist able to take advantage of the effects of structure perturbation for developing deeper insights into chemical behavior and for designing and understanding the molecular world as demanded by civilized societies.

Diarylmethyl Carbocation Reactivity in Cation Exchanged Zeolite Y. Geniece Hallett-Tapley, Norman P. Schepp and Frances L. Cozens. Submitted 2010, J. Can J. Chem.

Reactivity of Halo(pyridinium)carbenes. Reinaldo Moya-Barrios, Benjamin Fregeau and Frances L. Cozens. J. Org. Chem., 2009, 74, 9126-9131. PDF version.

Mark W. Konecny and Norman P. Schepp. Effect of steric bulk on the absolute reactivity of allene oxides. Org. Biomol. Chem., 2009, 7, 4437-4443. PDF version.

Absolute Reactivity of Halo(pyridyl)carbenes. Reinaldo Moya-Barrios, Frances L. Cozens and Norman P. Schepp. J. Org. Chem., 2009, 74, 1148-1155. PDF version.

Non-Resonant Two-Photon Photochemistry of a Barton ester, N-Phenylacetyloxy-2-pyridinethione. Norman P. Schepp, Christopher J.M. Green and Frances L. Cozens. Photochem. Photobio. Sci., 2009, 9, 110-113. PDF version.

Absolute Reactivity of Arylallyl Carbocations. Geniece Hallett-Tapley, Frances L. Cozens and Norman P. Schepp. J. Phys Org. Chem., 2009, 22, 343-348. PDF version.

Nonthermalized Excited States in Ru(II) Polypyridyl Complexes Probed by Ultrafast Transient Absorption Spectroscopy with High Photon Energy Excitation. Sherri A. McFarland, Karen A.W.Y. Cheng, Felix S. Lee, Frances L. Cozens and Norman P. Schepp. Can. J. Chem., 2008, 86, 1118-1125. PDF version.

Substituent and Solvent Effects on the beta-Heterolysis Reaction of beta-Hydroxy Arylethyl Radicals, Frances L. Cozens, Sandy F. Lancelot, and Norman P. Schepp. J. Org. Chem., 2007, 72, 10022 –10028. PDF version.

Influence of Alkali Metal Cation on the Distance of Electron Migration in Zeolite Y. A Nanosecond Laser Photolysis Study, Amy E. Keirstead, Norman P. Schepp, and Frances L. Cozens. J. Phys. Chem. C, 2007, 111, 14247-14252. PDF version.

Generation and Reactivity of Simple Aryl(chloro)carbenes within the Cavities of Non-acidic Zeolites. Reinaldo Moya-Barrios and Frances L. Cozens. J. Am. Chem. Soc., 2006, 128, 14836-14844. PDF version.

Resolution of Ultrafast Pyrene Excimer Emission Rise Times in Zeolites X and Y. Karen A.W.Y. Cheng, Norman P. Schepp and Frances L. Cozens. Photochemistry Photobiology special issue honoring Tito Scaiano 2006, 82, 132–138. PDF version.

Dynamics of the Transient Species Generated upon Photolysis of Diarylmethanes within Zeolites. Deprotonation and oxidation reactions. Suzanne Shea, Norman P. Schepp, Amy E. Keirstead and Frances L. Cozens. Can. J. Chem. special issue for Physical Organic Chemistry 2005, 83, 1637-1648. PDF version.

Reactivity of 4-Vinylphenol Radical Cations in Solution: Implications for the Biosynthesis of Lignans. Yan Evora-Rodriguez and Norman P. Schepp. Org. Biomol. Chem., 2005, 3, 4444-4449. PDF version.

Photochemical Generation of Simple Alkyl Allene Oxide in Solution. Leah Breen, Norman P. Schepp, Edward Tan. Can. J. Chem., 2005, 83,1347-1351. PDF version.

Picosecond Dynamics of Nonthermalized Excited States in Tris(2,2-bipyridine)-ruthenium(II) Derivatives Elucidated by High Energy Excitation. Sherri A. McFarland, Felix S. Lee, Karen A.W.Y. Cheng, Frances L. Cozens and Norman P. Schepp, J. Am. Chem. Soc., 2005, 127, 7065-7070. PDF version.

Ultrafast Dynamics of Pyrene Excimer Formation in Y Zeolites. Karen A. W. Y. Cheng, Norman P. Schepp, and Frances L. Cozens J. Phys. Chem. A, 2004, 108, 7132-7134. PDF version.

Generation and Absolute Reactivity of an Aryl Enol Radical Cation in Solution. Norman P. Schepp. J. Org. Chem., 2004, 69, 4931-493. PDF version.

Comparison of Activation Parameters for Ionization Reactions within Zeolites and in Aqueous Solution Norman P. Schepp, Wendy Monk, Frances L. Cozens J. Am. Chem. Soc., 2004, 126, 1012-1013. PDF version.

First Direct Observation of Reactive Carbenes in the Cavities of Cation-Exchanged Y Zeolites Reinaldo Moya-Barrios, Frances L. Cozens Org. Lett., 2004, 6, 881-884. PDF version.

Influence of Alkali Metal Cation on the Photoheterolysis of 9-Cyclopropyl-9-Fluorenol and the Reactivity of the 9-Cyclopropyl-9-Fluorenyl Cation in Non-Acidic Zeolites. Melanie O'Neill and Frances L. Cozens Can. J. Chem., 2003, 81, 647-659. PDF version.

Generation and reactivity of the radical cations of coniferyl alcohol and isoeugenol in solution, Norman P. Schepp, Yan Rodriguez-Evora, Can. J. Chem., 2003, 81, 799-806. PDF version.

Substituent Effects on the Ionization Reaction of beta-Mesylate Phenethyl Radicals. Sandy F. Lancelot, Norman P. Schepp and Frances L. Cozens Org. Biomol. Chem., 2003, 1, 1972-1979. PDF version.

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